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How mifepristone (Mifeprex) works
Mifepristone (Mifeprex) is an antiprogestin medication. It blocks the effects of progesterone, a natural sex hormone that’s important in starting and continuing a pregnancy. By blocking progesterone, mifepristone (Mifeprex) prevents a pregnancy from continuing.
Mifepristone (Mifeprex) is taken along with misoprostol (Cytotec), which causes your uterus to contract and push the pregnancy tissue out of your body. These two medications work together to end a pregnancy.
What is mifepristone (Mifeprex) used for?
- Ending a pregnancy that’s no more than 10 weeks along, when used together with misoprostol (Cytotec)
Mifepristone (Mifeprex) dosage forms
Tablet
Typical dosing for mifepristone (Mifeprex)
This medication is used together with misoprostol (Cytotec), and it must be taken as directed by your healthcare provider.
Day 1: Take one 200 mg tablet of mifepristone (Mifeprex) by mouth as a single dose. This is usually given to you at a provider’s office, clinic, or hospital.
Day 2 or 3 (between 24 and 48 hours after mifepristone (Mifeprex)): Take 800 mcg (four 200 mcg tablets) of misoprostol (Cytotec) by placing the tablets in your mouth alongside your cheeks and letting them dissolve. Place two tablets between the cheek and gum on the left side of your mouth. Place the other two tablets on the right side of your mouth in a similar way as the first two. Allow them to dissolve against your cheek for over 30 minutes. Then, swallow any remaining tablet bits with water or other liquid.
Note:
- Discuss with your provider about your medical abortion plan and dosing, since it might differ depending on your situation.
- You must follow up with your healthcare provider 1 to 2 weeks after taking mifepristone (Mifeprex) to make sure the pregnancy has ended completely.
Frequently asked questions about mifepristone (Mifeprex)
How much bleeding should I expect after taking mifepristone (Mifeprex) and misoprostol (Cytotec)?
Vaginal bleeding is normal during a medical abortion. At first, you might experience heavy bleeding, usually occurring 1 to 4 hours after taking misoprostol (Cytotec). Some people have had heavy bleeding for about 2 days. Once you pass the pregnancy tissue, it’s typical to see spotting (light bleeding) for 1 to 2 weeks, and up to 1 month or longer. But if you have bleeding that lasts a long time and is unusually heavy (soaking through two thick, full-size sanitary pads per hour for two consecutive hours), go to the emergency room right away and let your healthcare provider know. This can be a sign of an incomplete abortion, which needs to be treated immediately.
How long does it take to end a pregnancy with mifepristone (Mifeprex) and misoprostol (Cytotec)?
Where can I find mifepristone (Mifeprex)?
Do I take mifepristone (Mifeprex) at home?
Why is mifepristone (Mifeprex) only available from certain healthcare providers?
If I have an IUD (intrauterine device) and become pregnant, can I still use mifepristone (Mifeprex)?
Can I take mifepristone (Mifeprex) if I’m breastfeeding?
Read Pros and cons before Buy Mifeprex online
Pros
No surgery required to end pregnancy
Between 93% and 98% effective at ending pregnancy
Might be more affordable than a surgery to end pregnancy
Cons
Requires close contact with your healthcare provider to make sure the medication worked
Causes cramps, vaginal bleeding, and nausea
Risk of serious bleeding or infections
Pharmacist tips for before Buy Mifeprex online
Be sure to discuss with your healthcare provider about what to expect when taking mifepristone (Mifeprex), as there can be some side effects, such as cramping, nausea, and heavy bleeding.
You must follow up with your healthcare provider 1 to 2 weeks after taking mifepristone (Mifeprex). Your provider will need to examine you and make sure the medications worked and that there are no complications.
If you need to go to the emergency room or see a different provider for any reason during the process, make sure to let them know you’re currently having a medical abortion (e.g., take the Medication Guide for mifepristone (Mifeprex) with you).
Although mifepristone (Mifeprex) with misoprostol (Cytotec) works very well at ending a pregnancy, there’s a small chance that it won’t work. In this case, your healthcare provider will talk to you about your options to complete the abortion, like certain surgical procedures.
Let your healthcare provider know about all the medications you’re taking, including over-the-counter (OTC) medications and supplements, so they can make sure mifepristone (Mifeprex) is safe for you to take. These medications can affect how well mifepristone works or raise your risk of side effects. For example, taking mifepristone with a blood thinner called warfarin (Coumadin) can raise your risk of serious bleeding even more.
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With any medication, there are risks and benefits. Even if the medication is working, you may experience some unwanted side effects.
Contact your doctor immediately if you experience any of the following:
- Serious infection: fever that doesn’t go away (temperature of 100.4ºF or greater for more than 4 hours), severe stomach pain, stomach discomfort, weakness, nausea, vomiting, or diarrhea for more than 24 hours after taking misoprostol (Cytotec)
- Heavy vaginal bleeding for a long time
- Fainting
The following side effects may get better over time as your body gets used to the medication. Let your doctor know immediately if you continue to experience these symptoms or if they worsen over time.
Common side effects
- Nausea (51-75%)
- Weakness (55-58%)
- Fever or chills (48%)
- Vomiting (37-48%)
- Headache (41-44%)
- Diarrhea (18-43%)
- Dizziness (39-41%)
Other side effects
- Stomach pain or cramping
- Vaginal or uterine bleeding
- Anemia (low red blood cell count)
- Fast heart rate
- Lightheadedness
- Muscle pain
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